Dis Colon Rectum 1993 Jun;36(6):607-9. Mechanism of action. Description and Brand Names; Before Using; Proper Use; Precautions; Side Effects; Products and services. … The drug is not absorbed systemically and is excreted through the GI tract. sodium polystyrene sulfonate oral Common Brand(S): Kayexalate, Kionex, Marlexate Generic Name(S): sodium polystyrene sulfonate View Free Coupon 1993, 36 (6): 607-9. Colonic necrosis following sodium polystyrene sulfonate (Kayexalate)-sorbitol enema in a renal transplant patient. Dis Colon Rectum. Brand Names: US Kalexate [DSC]; Kayexalate [DSC]; Kionex; SPS Brand Names: Canada Kayexalate What is this drug used for? Sodium polystyrene sulfonate 1 g/kg/dose PR every 4 hours has been studied; however, the authors concluded that early continuous regular insulin infusion therapy for the treatment of non-oliguric hyperkalemia in very low birth weight infants is more effective than sodium polystyrene sulfonate. 0 reports. The drug is not absorbed systemically and is excreted through… Releases sodium ions that are replaced with potassium ions. Sodium Polystyrene Sulfonate (Oral Route) Print. Created by. Filter group. Available forms Available by prescription only Oral powder: 1.25 g/5 ml suspension Powder for oral or rectal administration: 454 g in 1-lb jar Rectal suspension: 1.25 g/5 ml suspension . Show all parts of this monograph; Indications and dose; Contra-indications; Cautions; Interactions; Side-effects; Pregnancy; Breast feeding; Renal impairment; Monitoring requirements; Directions for administration; Medicinal forms; Indications and dose. Match. Learn. Case Report Kayexalate-Induced Esophageal Ulceration in a Patient with Decompensated Cirrhosis: A Review of the Literature KishoreKumar ,1,2 HarishPatel,1,2 MuhammadSaad,2 AhmedBaiomi,1,2 andAnilDev1,2 1Division of Gastroenterology, BronxCare Hospital Center a Clinical Affiliate of Mt Sinai Health Systems and Academic Affiliate of Icahn School of Medicine, Bronx, NY 10457, USA Polystyrene sulphonates have been used since the late 50s, before the randomized controlled trial (RCT) era. Aspiration of this material is a rare occurrence, but when visualized in the alveolus, it has a characteristic microscopic appearance that is virtually diagnostic. Sodium polystyrene sulfonate is used to treat high levels of potassium in the blood, also called hyperkalemia. Sodium polystyrene sulfonate (Kayexalate). Drug information provided by: IBM Micromedex. Pharmacotherapeutics. Mechanism of Action. It affects the exchange of sodium and potassium in the body. sodium polystyrene sulfonate Kayexalate, SPS . It is a potassium-binding ion-exchange resin that can be administered orally (25 grams in 20% sorbitol) or rectally (50 grams in 20% sorbitol). All currently selected. Potassium-Removing Resins. Epub 2018 Apr 4. Retain in colon for at least 30-60 min (several hours if possible) After completing retention, use nonsodium colonic irrigant to remove remaining resin. Potassium-Removing Resins. Sodium polystyrene sulfonate is available as the brand name Kayexalate, as generic brands, and also as non-branded generics. The treatment of hyperkalemia includes removal of excess potassium from the body using cation exchange resins, e.g., sodium polystyrene sulfonate (Kayexalate) is one of the most practiced modalities in clinical medicine. Blood pressure and urine output are not of primary importance. If client does not have stools, the drug cannot work properly. Terms in this set (13) Therapeutic class. If playback doesn't begin shortly, try restarting your device. Therapeutic class. Potassium-Removing Resins. Before Using Potassium-removing resin used in treating hyperkalemia. Administered as an oral suspension, sodium polystyrene sulfonate lowers serum potassium levels by exchanging its sodium ions for potassium ions. Colonic perforation associated with sodium polystyrene sulfonate (Kayexalate) use Diagn Interv Imaging. 10.1007/BF02049870. Potassium-removing resin used in treating hyperkalemia . Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. OBJECTIVE: Sodium polystyrene sulfonate (kayexalate) is a cation-exchange resin given enterally for the treatment of hyperkalemia. Patients should take orally administered prescription and over-the-counter (OTC) medicines at least 3 hours before or 3 hours after sodium polystyrene sulfonate. Filter group. These are side effects of Kayexalate (Sodium Polystyrene Sulfonate) reported to the FDA by people taking it, and by doctors and pharmacists. CrossRefPubMed Scott TR, Graham SM, Schweitzer EJ, Bartlett ST: Colonic necrosis following sodium polystyrene sulfonate (Kayexalate)-sorbitol enema in a renal transplant patient. All currently selected. The combination of a sodium polystyrene sulfonate resin with a magnesium hydroxide-containing antacid consistently produced systemic alkalinization. However, it is unclear if it is beneficial and there is concern about possible side effects when it is combined with sorbitol. Pharmacokinetics. Three sample concentrations were analyzed: a control not subjected to potassium reduction, 0.5 g of Kayexalate per mEq K+ sample, and a 1 g/mEq K+ sample. Take or use sodium polystyrene sulfonate at around the same time(s) every day. Spell. METHODS: Sodium polystyrene sulfonate and enteral formula were mixed into a slurry and allowed to settle, and then the supernatant was decanted off and tested as samples. Sodium Polystyrene Sulfonate This information from Lexicomp explains what you need to know about this medication, including what it’s used for, how to take it, its side effects, and when to call your healthcare provider. PLAY. Pharmacologic classification: cation-exchange resin Therapeutic classification: potassium-removing resin Pregnancy risk category C . Polystyrene sulfonate affects the exchange of sodium and potassium in the body. For … Storage The lowest GoodRx price for the most common version of generic Kayexalate is around $12.96, 60% off the average retail price of $32.55. All ages 18-34 35-54 55+. Kayexalate (sodium polystyrene sulfonate) STUDY. By mouth. It is used to treat too much potassium in the body. Hyperkalemia is one of the most common electrolyte abnormalities encountered in clinical practice. 1993 Apr;12(3):77-9. Sodium polystyrene sulfonate was superior to placebo in the reduction of serum potassium levels (mean difference between groups, -1.04 mEq/L; 95% confidence interval, -1.37 to -0.71). 0 reports. Administer sodium polystyrene sulfonate as warm emulsion (body temperature) Gently agitate suspension during administration. 1. Hyperkalaemia associated with anuria or severe oliguria, and in dialysis patients . Normal serum potassium is 3.5 to 5.5 mEq/L. … Test. Sections. Flashcards. SODIUM POLYSTYRENE SULFONATE. Do not give this medicine orally (by mouth) to a newborn baby. Do not use the medicine orally or rectally in a baby who has slow digestion caused … jillian_holmes8. Find everything you need to know about Kayexalate (Sodium Polystyrene Sulfonate), including what it is used for, warnings, reviews, side effects, and interactions. Gravity. Our general interest e-newsletter keeps you up to date on a wide variety of health topics. Proper Use. Write. CrossRef PubMed. Pharmacokinetics. S2988 Sodium Polystyrene Sulfonate (Kayexalate)-Induced Gastric Pneumatosis: A Rare Side Effect Suga, Herman DO 1 ; Dasu, Neethi R. DO 1 ; Weston, Joshua DO 1 ; Joo, Lucy M. DO 1 ; Blair, Brian DO 1 ; Khalid, Yaser DO 1 ; Dasu, Kirti 2 It is used to treat high potassium levels. Report of a case and review of the literature. Sodium polystyrene sulphonate (SPS; Kayexalate ®) and calcium polystyrene sulphonate (CPS; Resikali ®) are commonly used cation-exchange resins for the treatment and control of hyperkalaemia. It is used as a potassium binder in acute and chronic kidney disease for people with hyperkalemia (abnormal high blood serum potassium levels). Take or use sodium polystyrene sulfonate exactly as directed. Sodium polystyrene sulfonate is usually taken or used one to four times a day. SODIUM POLYSTYRENE SULFONATE takes potassium out of the body by binding to it in the intestines. This medicine is available only with your doctor's prescription. Free E-newsletter Subscribe to Housecall. Take this … Sodium Polystyrene Sulfonate(Kayexalate) generic is a potassium-removing resin, prescribed for hyperkalemia (without ECG changes). Polystyrene sulfonate is usually supplied in either the sodium or calcium form. Noerr B. PMID: 8474418 [PubMed - indexed for MEDLINE] MeSH Terms Compare potassium binders. Report of a case and review of the literature. Everyone Men Women. Sodium polystyrene sulfonate ( C0142915 ) Definition (NCI) A potassium ion exchange resin composed of benzene-diethyl polymer with ethenyl-benzene, sulfonated, sodium salt. Substitution of calcium phase resin for sodium phase resin resulted in loss of the alkalinizing effect of the regimen. Sodium polystyrene sulfonate can be given as a liquid by mouth, through a stomach feeding tube, or as a rectal enema. Sodium polystyrene sulfonate 1 g/kg/dose PR every 4 hours has been studied; however, the authors concluded that early continuous regular insulin infusion therapy for the treatment of non-oliguric hyperkalemia in very low birth weight infants is more effective than sodium polystyrene sulfonate. Neonatal Netw. SODIUM POLYSTYRENE SULFONATE, USP Cation-Exchange Resin DESCRIPTION KAYEXALATE, brand of sodium polystyrene sulfonate is a benzene, diethenyl-polymer, with ethenylbenzene, sulfonated, sodium salt and has the following structural formula: The drug is a cream to light brown finely ground, powdered form of sodium polystyrene sulfonate, a cation-exchange resin prepared in the sodium … Videos you watch may be added to the TV's watch history and influence TV recommendations. Jul-Aug 2018;99(7-8):507-509. doi: 10.1016/j.diii.2018.02.003. The nurse would already expect changes in T waves with hyperkalemia. Kayexalate (sodium polystyrene sulfonate) Therapeutic class. Kayexalate causes potassium to be exchanged for sodium in the intestines and excreted through bowel movements. Sodium polystyrene sulfonate (SPS or Kayexalate) is a resin that binds and exchanges potassium for sodium and is licensed for oral or rectal administration to treat elevated serum potassium levels; however, use can be limited due to poor palatability and gastrointestinal or metabolic adverse effects, as well as concern for enteral feeding tube obstruction [2, 3]. Pharmacotherapeutics. Sign up now . Polystyrene sulfonate is used to treat high levels of potassium in the blood, also called hyperkalemia. interaction studies with potassium-lowering drug Kayexalate (sodium polystyrene sulfonate) issued on October 22, 2015. Resin for sodium phase resin resulted in loss of the regimen through the GI tract ask doctor. ) era used one to four times a day severe oliguria, and also as non-branded generics an! 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